The Role of Platelet-Rich Plasma in Bone Regeneration in Patients with Osteoporotic Fractures: A Literature Review
Alyssa Cevetello, Kyle Taylor, Janae Rasmussen*, Layla Aljoudi, Jacob Ritter, Rachel Yim, Donia Javidi and Behzad Maher
ABSTRACT
Platelet-rich plasma (PRP) is an innovative biologic therapeutic treatment used in orthopedics to enhance tissue repair and accelerate the healing process. PRP promotes the release of growth factors and cytokines involved in wound healing. It has extensive clinical applications and has become increasingly prevalent in the treatment of various orthopedic-related injuries. Osteoporosis is an increasingly common comorbidity in orthopedics and is a significant factor that increases susceptibility to fractures. The risk of developing osteoporosis rises with age, making it more prevalent in the geriatric population. Since osteoporotic fractures are a frequent consequence of osteoporosis, selecting appropriate treatment modalities remains a critical aspect of patient care in this population. As PRP continues to gain traction in orthopedics, it is necessary to study its therapeutic effects on bone regeneration in osteoporotic fractures. This literature review aims to evaluate whether PRP provides clinical benefits in treating osteoporotic fractures based on recent investigations.
