A Comparison of the Risk Factors and Clinical Manifestations of Barrett’s Oesophagus in Young and Old People
Julia Bullock
ABSTRACT
Introduction: Ageing, being a man, being obese, and having chronic reflux symptoms are risk factors for Barrett’s oesophagus (BE). This study’s objective was to compare the risk variables and symptom presentations between young and older Chinese BE patients.
Methods: From December 2016 through May 2019, prospective data from the VGHTC were gathered. Data from instances that were younger than 60 years old and older than 60 years old were gathered and compared.
Results: The 67 subjects enrolled included 31 (46.3%) senior patients and 36 (53.7%) young patients. The majority of the BE individuals (63.6–77.4%) were male and had short-segment BE (94.4–93.5%). The prevalence of obesity, waist circumference, and BMI were comparable between the two groups. Hiatal hernia rates were non-significantly higher in the older cases (58.1% vs. 38.9%, P=0.117). Dysplasia was present in two young (5.6%) and two older (6.5%) patients. Adenocarcinoma was present in one elderly patient (3.2%). Typical reflux symptoms were present in the majority of patients (58.1%–61.1%), and older patients were more likely to smoke than younger patients. Both groups’ SF-12 results were comparable.
Conclusion: The presentations of young and old BE patients were comparable. More research is required.
